This article explore why Seresilk stands as the world’s most potent silk skincare.
Travel along a silk road of discovery...
Silk’s powerful skincare properties have been celebrated for centuries. On the ancient Silk Road, women of Seres were fabled for their hands, as soft as the silk they once cultivated.
Today, market-leading brands such as Tatcha, Peter Thomas Roth and Elemis use silk across their formulations.
But why don't more brands use silk?
There is a problem. Silk production, led by China is typically cruel and sees the needless killing of hundreds of millions of silkworms yearly across Asia.
The Seresilk difference.
The hero ingredient behind each Australian Seresilk formulation is the proprietary Hydrolysed Silk Complex HSC01-A™. Over 2× more powerful than market alternatives, the laboratory-formulated blend unlocks a rare blend of di- and tripeptides alongside silk’s native 18 free amino acids.
What are the benefits of silk in skincare?
Silk’s hydrolysed peptides work deeply with your skin to address its concerns. By soothing and calming irritation and reducing inflammation, peptides target fine lines and wrinkles, while supporting natural repair to leave skin soft, smooth, and hydrated. Moisture retention and barrier reinforcement further enhance resilience, resulting in skin that looks radiant, feels supple, and is strengthened from within — all with the gentle, hypoallergenic touch that only silk can provide.¹
How is Hydrolysed Silk Complex HSC01-A™ different?
Hydrolysed Silk Complex HSC01-A™'s power is derived from its uniquely cruelty-free mulberry silk. The rare pristine and harmonious conditions of Australia's environment give its silk an exceptional quality.
Silk itself is among nature’s rarest marvels: nature's strongest yet lightest fibres, the textile of choice for royals over millennia, powerful medical applications, and used by aerospace engineers.
An art of artisans, silk production is incredibly complex and requires years of practice and mastery. The quality of silk is shaped by numerous factors, both guided and inherent to the silkworm’s delicate life cycle.
As part of Australian Silk Group, Seresilk collects the empty silk cocoons from existing production. The unique intersection of wild and pristine conditions in Australia's natural environment is rare and precious, inspiring silk of the highest quality and giving each cocoon its world-leading strength and purity.
Before entering the laboratory, each cocoon is expertly selected, where the silk is prepared for the proprietary Seresilk hydrolysis process whereby it is subject to reflux conditions.
Over a 24-hour period, each cocoon slowly melts and transforms into a luminous liquid shining with subtle hues of soft gold. Cooled to room temperature, the final result is Hydrolysed Silk Complex HSC01-A™: a powerful blend of 18 free amino acids and di- and tripeptides.
Sharing a 90% rate of affinity with human skin and echoing its natural-moisturising factors, these amino acids rebuild the intercellular lipid matrix, while bioactive peptides prompt fibroblasts to support elasticity and renew the skin’s youthful luminosity.
Table: Competitor analysis of amino acid profiles between hydrolysed silk formulations.
| Amino Acid | HSC01‑A™ | Trulux | Crosilk G |
|---|---|---|---|
| Alanine | 629 (24.98%) | 324 (28.47%) | 32.50% |
| Arginine | 48 (1.90%) | 10 (0.84%) | 0.70% |
| Aspartic Acid | 99 (3.93%) | 26 (2.28%) | 3.50% |
| Cystine | 0 (0.00%) | 3 (0.23%) | 0.02% |
| Glutamic Acid | 65 (2.58%) | 23 (2.03%) | 2.60% |
| Glycine | 769 (30.53%) | 405 (35.50%) | 38.40% |
| Histidine | 0 (0.00%) | 4 (0.33%) | 0.10% |
| Isoleucine | 18 (0.71%) | 9 (0.81%) | 0.70% |
| Leucine | 17 (0.67%) | 7 (0.60%) | 1.00% |
| Lysine | 23 (0.91%) | 6 (0.50%) | 0.30% |
| Methionine | 7 (0.27%) | 1 (0.13%) | 0.00% |
| Phenylalanine | 34 (1.35%) | 14 (1.23%) | 0.20% |
| Proline | 20 (0.79%) | 4 (0.36%) | 1.00% |
| Serine | 489 (19.43%) | 137 (12.03%) | 14.60% |
| Threonine | 42 (1.67%) | 12 (1.08%) | 1.40% |
| Tryptophan | 0 (0.00%) | 4 (0.36%) | 0.00% |
| Tyrosine | 200 (7.93%) | 118 (10.31%) | 0.40% |
| Valine | 59 (2.34%) | 33 (2.92%) | 2.60% |
| Total Protein | 2520 mg (2.52%) | 1140 mg (1.14%) | Unknown |
The amino acid composition of silk proteins can play a significant role in how each formulation impacts skin health and understanding these differences can help guide the choice of products that may suit specific skincare needs. The results attributed to competitor brands are freely available online given the strict disclosure requirements common in the skincare industry.
How to interpret the data?
Not only is the Hydrolysed Silk Complex HSC01-A™ total protein content significantly higher, but its amino acid profile stands out due to its balanced composition when compared to Crosilk G.
The hero ingredient across each Seresilk formulation, Hydrolysed Silk Complex HSC01-A™'s unique composition rebuilds the skin's intercellular lipid matrix for the world's most potent silk skincare that is designed to soothe and calm, reduce inflammation, support skin repair, retain moisture, and reinforce the skin’s natural barrier, all while being naturally hypoallergenic.
Breaking down some of the key amino acids in Hydrolysed Silk Complex HSC01-A™.
Glycine (30.53%):
Glycine is essential for promoting hydration and improving skin elasticity. It helps maintain the skin’s moisture barrier, keeping the skin plump, smooth, and hydrated, enhancing overall skin health.
Alanine (24.98%):
Alanine plays a key role in moisture retention, supporting the skin’s ability to stay hydrated throughout the day. This makes Hydrolysed Silk Complex HSC01-A™ an excellent choice for keeping skin nourished and rejuvenated.
Serine (19.43%):
Hydrolysed Silk Complex HSC01-A™ stands out with its notably higher serine content. This amino acid plays a key role in enhancing hydration, supporting collagen production, and improving skin elasticity. The increased serine concentration in HSC01-A™ helps to maintain moisture balance, leading to a more supple and plump appearance. The combination of serine and other balanced amino acids ensures that HSC01-A™ provides comprehensive nourishment, repair, and protection for the skin.
Tyrosine (7.93%):
Hydrolysed Silk Complex HSC01-A™ has a significantly higher total protein content when compared to Trulux, contributing to the skin’s defence by aiding melanin production. This helps protect the skin from UV radiation and environmental stress, promoting a healthy, even skin tone. The higher protein content in Hydrolysed Silk Complex HSC01-A™ ensures a more potent dose of tyrosine for better skin protection and resilience.
Aspartic Acid (3.93%):
Aspartic acid plays a crucial role in detoxifying the skin and promoting moisture retention. Higher levels of this amino acid compared to Trulux and Crosilk G make Hydrolysed Silk Complex HSC01-A™ particularly effective in maintaining skin hydration and promoting a fresh, revitalised appearance. Aspartic acid also supports the skin’s ability to renew itself, helping to maintain a youthful, glowing complexion.
Arginine (1.90%):
Compared to Trulux and Crosilk G, which contain much lower concentrations of arginine, Hydrolysed Silk Complex HSC01-A™ arginine helps improve blood circulation, promoting the delivery of nutrients to skin cells. This accelerates healing, boosts hydration, and encourages a healthier, radiant complexion. Its role in skin rejuvenation makes Hydrolysed Silk Complex HSC01-A™ a superior choice for long-term skin health.
Appendix:
¹Clinical studies show topical silk protein enhances hydration, reduces water loss, and smooths the skin surface (PMC, 2006).
- Not all silk used across skincare is equal. The following factors impact its quality:
- Hydrolysis procedures, and
- The diet and environmental conditions of the silkworm contributing to its overall wellbeing and consequent quality of silk.
- Peptides form when protein chains remain partially intact, allowing them to act as signalling molecules that stimulate collagen production and reinforce skin structure. Acting as messengers, the peptides trigger the skin’s natural repair processes to improve texture and maintain a healthy, balanced complexion. Meanwhile, free amino acids result from complete protein breakdown, providing the fundamental building blocks that strengthen the skin’s natural barrier, improving hydration and preventing moisture loss, which keeps the skin soft and nourished.
- The majority of peptides in hydrolysed silk are tripeptides, with an average molecular weight that typically sits at approximately 300 Da. Seresilk hydrolysed silk also includes dipeptides (two amino acids), and larger peptides, each contributing to a synergy of various-sized peptides that nurture and support the skin barrier. Keeping in mind that peptides under 500 Da generally penetrate the skin well, the variety of peptides in a single hydrolysed silk formulation offers significant benefits at different levels by acting at both the surface and deeper layers of the skin.